Brain Training Is Important For Smart Aging

Brain Training That Provides Visual Feedback

How Thinkie Helps you in 3 Steps

Thinkie's Real-Time Neurofeedback

Closeup of Thinkie device in pink, being held in hands.

01 Measure

The Thinkie sensor detects brain blood oxygen levels safely and non-invasively.

Closeup of Brain meter score on iPhone device, showing 46 Thinkie points and an Excellent score for brain age.

02 Visualize

Real-time feedback shows focus and mental effort.

Closeup of Brain Meter in action on iPad while a user plays a guitar. The Thinkie device shows current brain activity while playing guitar.

03 Train Smarter

Thinkie’s visual feedback and data insights help you get more out of every session.

Learn More
functional near-infrared spectroscopy

How Does the Sensor Work?

Diagram showing functional near-infrared spectroscopy (fNIRS) through skin and skull layers. Near-infrared light irradiation penetrates the tissue (shown by downward arrow) and is detected as it exits (shown by upward arrow). A yellow circle indicates the area of neural activity beneath the skull. Three numbered annotations explain: 1) An increase in neural activity causes an increase in blood flow, 2) Due to more hemoglobin, light throughput is decreased, 3) The fNIRS sensor detects this change.

Thinkie Measures Near-Infrared Light

Diagram showing functional near-infrared spectroscopy (fNIRS) through skin and skull layers. Near-infrared light irradiation penetrates the tissue (shown by downward arrow) and is detected as it exits (shown by upward arrow). A yellow circle indicates the area of neural activity beneath the skull. Three numbered annotations explain: 1) An increase in neural activity causes an increase in blood flow, 2) Due to more hemoglobin, light throughput is decreased, 3) The fNIRS sensor detects this change.

fNIRS technology works by measuring near-infrared light as it passes through the brain, detecting changes in oxygen levels within hemoglobin. The Thinkie app interprets these shifts in cerebral blood flow volume as increases or decreases in neural activity.

These measurements reveal how active the brain is at any given moment through a continuous feedback loop. By capturing ongoing changes in oxygenated blood flow, the Thinkie sensor provides real-time insights into your brain’s engagement. This method of measurement is recognized by the U.S. Food and Drug Administration (FDA) as a standard for assessing cerebral hemodynamics (21 CFR § 882.5050).

Brain diagram

Why Pre-Frontal Cortex?

A graph depicting one's brain activity score on a colorful backdrop. The Brain Score is the average of ever 1 sec.

Prefrontal cortex the part of the brain responsible for focus, decision-making, memory, and self-control. This region is like the brain’s “control center,” guiding how we think, plan, and stay attentive.

By monitoring blood flow in the prefrontal cortex, Thinkie can give you the most relevant insights into your mental effort—helping you know when you’re fully engaged and pick the right exercise for you.

How Thinkie Provides Effective Cognitive Training

Icon of a magenta brain with three interlocking gears inside, labeled 'cognitivetraining_image'. Below the icon is text reading 'Blood Flow increase in Pre-frontal Cortex (Your Thinkie Part)'.
Blood Flow increase in Pre-frontal Cortex (Your Thinkie Points) reflects the intensity of your training.
Icon of a magenta trophy with a star on the front and two handles. Below the icon is text reading 'Performance Benchmark (Your...' with the text appearing to be cut off.
Performance Benchmark (Your Brain Age) validates the effectiveness of your training

The Thinkie app measures the intensity of your training by measuring your brain’s increase in blood flow, and monitor the effectiveness by tracking your cognitive performance.

Follow the real-time color coded signals during your training session to find the best way to engage your brain.

Check your brian age regularly to track your progress. You can expect to see changes after regular use for 4 weeks.

Line graph titled 'Brain Age improvement after regular use of Thinkie' showing brain age changes over 37 months. The line starts at 0.0 and descends to approximately -25.0 on the y-axis. Three key milestones are marked: at 12 months, a magenta arrow shows 10.6 years younger improvement; at 24 months, an orange arrow shows 12.9 years younger (over 2 years, 60 people); at 36 months, a yellow arrow shows 21.0 years younger (over 3 years, 13 people). The bottom of the chart shows participant demographics by age group: 40s: 5 people, 50s: 19 people, 60s: 36 people, 70s: 81 people, 80s: 35 people, 90s: 2 people, Total: 178 people.

Source: Analysis of real-world data from 178 users in Japan using the Brain Age mental speed assessment.

What's Your Brain Age?

Thinkie’s Brain Age test is a gamified cognitive test that assesses your processing speed, working memory and attention.

Published Studies

Bar chart titled 'The effect of neurofeedback on cognitive abilities' showing four panels comparing three conditions: brain training with neurofeedback (magenta), brain training without neurofeedback (orange), and tetris without neurofeedback (blue). Processing Speed panel shows values of approximately 18, 15, and 7 respectively. Working Memory panel shows values of approximately 1.5, 0.7, and 0.7. Attention panel shows values of approximately 13, 3, and 3. Episodic Memory panel shows values of approximately 2.5, 0.5, and 0.4. Across all four cognitive measures, brain training with neurofeedback demonstrates substantially higher improvements compared to the other two conditions.
Brain Training is Better with Neurofeedback

2021 STUDY TOHOKU UNIVERSITY & UNIVERSITÉ DE LORRAINE

Cognitive Training with Neurofeedback Using NIRS Improved Cognitive Functions in Young Adults: Evidence from a Randomized Controlled Trial

This randomized controlled trial investigated the effects of cognitive training with neurofeedback (CT-NF) using near-infrared spectroscopy (NIRS) on cognitive functions in young adults. Major findings include that CT-NF training leads to greater improvements in working memory, processing speed, and attention. Subjects' improvements were associated with increased brain activity in the dorsolateral prefrontal cortex.

Source: Brain Sci. Cognitive Training with Neurfeedback Using NIRS Improved Cognitive Functions in Young dults: Evidence from a Randomized Controlled Trial 2022, 12, 5.

Thinkie Brain Games Are Better Than Tetris

2021 STUDY - UCSB

This report provides methods, measures and results pertaining to the Effects of Cognitive Training (ECT) study, whose aim is to investigate the effects of engaging in 4 weeks of app-based ABC program (Thinkie) vs. playing Tetris. The study, sponsored by Mitsui, was conducted by Drs. Acevedo and Collins in the Department of Psychological & Brain Sciences at the University of California, Santa Barbara. Data collection for this project began in May 2021 and ended in December 2021.

Results
The study's results showed that the treatment group demonstrated significant improvements in memory, verbal memory, and composite cognitive function, while both groups showed improvements in processing speed and executive function. This suggests that cognitive training program with neurofeedback, particularly with ABC exercises, can enhance cognitive function in older adults.

Methods
All procedures were reviewed and approved by the Human Subjects Committee (the IRB) of the University of California, Santa Barbara (IRB #: 65 - 20 - 0856). Participants were 125 right-handed individuals, ages 54-84, living independently and in relatively good health. Participants were recruited via listservs, community groups, social media, advertisements in the Santa Barbara community, and via independent living organizations.

Source: Effects of Cognitive Training Study: Final Reprot by Mitsui by Acevado, B & Collins, N. (January, 2022)

It Matters What Brain Training Activities You Do

2020 STUDY TOHOKU UNIVERSITY

You might think doing virtually any on-screen activity would equally benefit the brain, but the results of this study speak volumes to the contrary. Among its key findings is that the ability to measure the effects of a mental activity is critical to meaningful brain training. That is why fNIRS neurofeedback technology is so important, and why we use it in the Thinkie system.

Source: Brain Sci, Dorsolateral Prefrontal Cortex Activity during a Brain Training Game Predicts Cognitive Improvements after Four Weeks Brain Training Game Intervention: Evidence from a Randomized Controlled Trial 2020, 10, 560

Meet The Scientist

DR Kawashima
the brain behind the thinkie brain games

Dr. Ryuta Kawashima

01
Tohoku University • Japan
MD/School of Medicine
Executive Director/Smart Aging Research Center Professor/Division of Developmental Cognitive Neuroscience
02
Karolinska Institute • SwedenGuest Researcher
03
Specialty Training in Neurophysiology
04
Expert in Brain Imaging
05
Published Neuroscientist
06
Famous for Brain Age puzzle games by Nintendo
27 Years In Development

fNIRS Technology Miniaturized

Close-up photograph of hands holding a Thinkie neurofeedback headband device. The device features a dark gray sensor unit with two square button indicators on its face and a blue elastic strap attached to it. The background is softly blurred.

The Thinkie sensor, developed over a span of 27 years and based on functional Near-Infrared Spectroscopy (fNIRS) technology, continually measures the blood flow in the prefrontal cortex as the activity is taking place, and provides an immediate visual representation of that brain activity level.

Thinkie Inc has been able to adapt this complex technology to a safe product that can be used by people of all ages to monitor their activities to improve mental acuity.

The Evolution Of The Ultra-Compact Thinkie Sensor From 1995 To Present Day

fNIRS Development Timeline

1985

Medical School Graduate

Dr. Kawashima graduates from Tohoku University School of Medicine with M.D.

PhD Achievement
1989

Doctorate Achievement

Dr. Kawashima is awarded Ph.D. in Medicine from Tohoku University.

Karolinska Institute
1991

International Research

Dr. Kawashima becomes visiting researcher at Karolinska Institute, Sweden, majoring in Dementia Prevention and Functional Brain Imaging.

Hitachi Research
1995

Pioneering Brain Research

Dr. Kawashima begins research on brain measurement technology using near-infrared light (optical topography technology) at Hitachi Central Research Laboratory.

SAIDO Learning
2001-2003

SAIDO Learning Development

Dr. Kawashima leads joint development of SAIDO learning between Tohoku University and Kumon.

Nintendo Partnership
2005

Nintendo Brain Training Launch

Dr. Kawashima and Nintendo release Brain Training for Nintendo DS, selling 36 million copies worldwide thus far.

Wearable Technology
2007

Wearable Technology Prototype

Hitachi announces prototype of wearable optical topography technology.

Business Unit
2009

Business Unit Establishment

Brain Science Business Unit established within Hitachi's New Business Development Headquarters. Launch of compact 2-channel NIRS (HOT-121).

NIRS Development
2011

Ultra-Small NIRS Development

Tohoku University and Hitachi collaborate on development of ultra-small NIRS sensor which eventually leads to founding of NeU Corporation and Thinkie sensor as its principal technology.

Hitachi High-Tech
2014

Technology Transfer

Thinkie prototype transferred to Hitachi High-Technologies (now Hitachi High-Tech).

NeU Establishment
2017

NeU Establishment

NeU Inc. established with investments from Tohoku University and Hitachi High-Tech.

Excellence Award
2019

Excellence Award

NeU wins Excellence Award at Japan Healthcare Business Contest 2019.

Innovation Award
2021

Innovation Recognition

NeU selected as finalist for Innovation of the Year - Dementia Technology Solution award.

US Establishment
2023

U.S. Expansion

Thinkie Inc. established in USA.

Consumer Launch
2024

Consumer Market Entry

Thinkie begins direct-to-consumer sales.

Science Your Brain.

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